ATS 2024 Highlights Respiratory Structure and Function Early Career Professionals If you or someone you know would like to be featured as an ATS RSF ECP please email Carolyn Wang (carolyn.wang@hli.ubc.ca ) Get to know members of the RSF Assembly Afzaal N. [...] My research mainly deals with investigating the therapeutic efficacy of biological therapy and chemical agents in developmental pulmonary disorders. I mainly focus on novel compounds that can activate the transcription factors involved in the normal lung development and/or tissue repair after injury. [...] In addition, I also deal with biological therapy which is one of the novel approaches to cure the rare developmental disorders. Validating and/or improving the efficiency of the cell therapy approaches will be a significant contribution in the field. [...] This research is a significant contribution towards unravelling the pharmacological importance of drugs and biological agents which could lead to development of new therapies in rare developmental disorders. Where do you see yourself in 5 years? In the next five years, I aspire to continue my research journey towards in-depth analysis of lung disorders and finding novel compounds from natural o [...] What do you find is the major benefit of RSF Assembly Membership? [...] Networking, friends. Email: amohamm@arizona.edu LinkedIn: Please follow us on LinkedIn and X @ATS_RSFObjective: To improve the efficacy of endothelial cell therapy in mouse model of bronchopulmonary dysplasia (BPD). [...] Following hyperoxia, recipient mice were transplanted with FACS sorted cKIT+ EPCs, rAM or combination of both through retro-orbital injection. [...] In another set of mice, rAM were depleted using chlodronate- containing liposomes prior to transplantation of cKIT+ EPCs. Recipient mice were harvested at P18 to analyze the retention of donor-derived endothelial cells in lungs using flow cytometry. [...] This property of rAM may lead to the development of new cell therapies directed on enhancing the engraftment and efficacy of EPCs therapy in BPD. Afzaal N. [...] Mohammed, PhD Research Scientist III Department of Child Health University of Arizona College of Medicine-Phoenix If you or someone you know would like to be featured as an ATS RSF ECP please email Carolyn Wang (carolyn.wang@hli.ubc.ca ) Co-Transplantation of Alveolar Macrophages Improves the Efficacy of Endothelial Progenitor Cell Therapy in Mouse Model of Bronchopulmonary Dysplasia Please fol
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