Mpox Surveillance - REPORTING PROTOCOL FOR AFRICAN UNION MEMBER STATES - August 2024

The protocol also underscores the importance of genomic sequenc- ing to track the evolution and spread of the mpox virus, urging countries to systematically collect and share ge- nomic data to support global surveillance and outbreak management efforts. [...] The ever, initial research and reports from affected coun- first human case of mpox was recorded in 1970 in the tries suggest that the viral mutation found in clade IIb Democratic Republic of the Congo (DRC) and has sub- and clade Ib is both necessary for sustained human-hu- sequently been recognized as an endemic disease in man spread and is also associated with less severe dis- several central a. [...] In ad- encouraged to share all MPXV genome data dition to the potential use of sequencing for diagnosis, with the respective Ministries of Health, Africa MPXV genome can provide valuable information to help CDC, WHO, and the global scientific community understand the origins, epidemiology, and characteris- to enhance national and regional genomic sur- tics of the virus: for example, the origins of. [...] Number of contacts completed 21 days * The data should be disaggregated by age, sex, comorbidities and occupation Reporting to Africa CDC Countries are encouraged to share the case-based data with the African CDC and the WHO using the validated variables of the Member States (Table 3 and Table 4). [...] • Proportion of confirmed and probable cases with Submission of the case-based information should be complete demographic information done by the national surveillance or mpox focal point(s), • Proportion of confirmed and probable cases with who will compile the reports and upload into the EMS or complete clinical and risk factor information forward it to the Africa CDC ebs@africacdc.org C.